Development of complex chromosome rearrangements in a patient with ALL
RNDr. Andrea Blahová, Alexandra Oravcová, Kristína Lengyelová, RNDr. Renáta Lukačková, Kristína Juríková, Lucia Žideková, Ľubica Majerová, Renata Lukačková, Lenka Cicmanová-Palčová
In the report, we describe an interesting case of 63-year old man with diagnosis of acute lymphoblastic leukaemia. We examined karyotype with cytogenetic methods and...
RNDr. Andrea Blahová, Nikola Chovanová, Kristína Lengyelová, MUDr. Lenka Oravcová, Kristína Juríková, Mgr. Jakub Petrík, Michaela Patáková-Zrubcová, RNDr. Renáta Lukačková
The myelodysplastic syndrome (MDS) is a heterogeneous group of clonal haematopoietic disorders originated in the bone marrow. It is characterized by ineffective haematopoiesis, dysplastic changes...
Introduction: Acute myeloid leukemia (AML) is a phenotypically and genetically heterogenous clonal disease of blood-forming progenitor cells which causes rapid and uncontrolled proliferation of pathological...
Keywords: AML, cytogenetics, FISH, KMT2 gene, molecular analysis, translocation
