{"id":2200,"date":"2020-09-08T08:50:18","date_gmt":"2020-09-08T06:50:18","guid":{"rendered":"https:\/\/www.newslab.sk\/alveolarna-echinokokoza-na-slovensku\/"},"modified":"2020-09-08T08:53:07","modified_gmt":"2020-09-08T06:53:07","slug":"alveolar-echinococcosis-in-slovakia","status":"publish","type":"post","link":"https:\/\/www.newslab.sk\/en\/alveolar-echinococcosis-in-slovakia\/","title":{"rendered":"Alveolar echinococcosis in Slovakia"},"content":{"rendered":"<p><span style=\"color: #ff0000;\"><strong>*All tables, charts, graphs and pictures that are featured in this article can be found in the .pdf attachment at the end of the paper.<\/strong><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong>Alveol\u00e1rna echinokok\u00f3za u \u013eud\u00ed na Slovensku<\/strong><\/p>\n<p>Prv\u00e9 dva pr\u00edpady ochorenia \u010dloveka boli na Slovensku zaznamenan\u00e9 v roku 2000 a 2002(1,2). N\u00e1sledne do\u0161lo k postupn\u00e9mu n\u00e1rastu incidencie ochorenia, pri\u010dom do roku 2011 boli na Parazitologickom \u00fastave SAV zisten\u00e9 ro\u010dne jeden a\u017e tri pr\u00edpady ochorenia a od roku 2012 narast\u00e1 po\u010det potvrden\u00fdch pr\u00edpadov o p\u00e4\u0165 a\u017e desa\u0165 za rok. Doteraz bolo ochorenie potvrden\u00e9 u 80 pacientov, pri\u010dom v\u00e4\u010d\u0161ina z nich poch\u00e1dzala z endemick\u00fdch oblast\u00ed severn\u00fdch regi\u00f3nov Slovenska (pre\u0161ovsk\u00fd, \u017eilinsk\u00fd a tren\u010diansky kraj) (obr\u00e1zok 1). Priemern\u00fd vek v \u010dase potvrdenia infekcie bol 53,4 \u00b1 16,0 roka a v\u00fdskyt ochorenia bol \u010dastej\u0161\u00ed u \u017eien (47 pr\u00edpadov) ako u mu\u017eov (33 pr\u00edpadov). Zauj\u00edmav\u00fd je v\u0161ak aj v\u00fdskyt ochorenia u 7 (8,75 %) pacientov mlad\u0161\u00edch ako 20 rokov (najmlad\u0161\u00ed pacient mal 6 rokov), \u010do sved\u010d\u00ed o vysokom infek\u010dnom tlaku vonkaj\u0161ieho prostredia, preto\u017ee AE sa pova\u017euje za ochorenie star\u0161ieho veku a jeho v\u00fdskyt u det\u00ed v celoeur\u00f3pskom meradle, ale aj vo vysoko endemick\u00fdch oblastiach \u010c\u00edny dosahuje len asi 2 %(3,4). Fylogenetick\u00e9 anal\u00fdzy vzoriek DNA z\u00edskan\u00fdch od 4 pacientov potvrdili, \u017ee v\u0161etky \u0161tyri izol\u00e1ty patria k eur\u00f3pskym haplotypom E. multilocularis, ozna\u010dovan\u00fdm ako genotyp M2. Zistilo sa navy\u0161e, \u017ee izol\u00e1ty poch\u00e1dzaj\u00face od pacientov z v\u00fdchodn\u00e9ho a stredn\u00e9ho Slovenska sa medzi sebou mierne l\u00ed\u0161ia(5), \u010do nazna\u010duje potrebu \u010fal\u0161\u00edch anal\u00fdz vzoriek z\u00edskan\u00fdch od \u013eud\u00ed aj zvierat (obr\u00e1zok 1).<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Echinococcus multilocularis na Slovensku<\/strong><\/p>\n<p>Na Slovensku bol E. multilocularis u l\u00ed\u0161ky hrdzavej po prv\u00fdkr\u00e1t zaznamenan\u00fd v roku 1999. Dlhodob\u00e9 prieskumy realizovan\u00e9 na \u00fazem\u00ed Slovenska v rokoch 2002 \u2013 2011 dok\u00e1zali, \u017ee priemern\u00e1 prevalencia parazita u l\u00ed\u0161ok hrdzav\u00fdch je asi 30 % a v oblasti Tatransk\u00e9ho n\u00e1rodn\u00e9ho parku (TANAP) dosahuje 45 %. Z\u00e1rove\u0148 boli v severn\u00fdch okresoch pre\u0161ovsk\u00e9ho a \u017eilinsk\u00e9ho kraja identifikovan\u00e9 endemick\u00e9 oblasti, kde prevalencia p\u00e1somnice dosahuje miestami a\u017e 60 %(6). V\u00fdskyt infekcie je v\u0161ak \u010dast\u00fd aj u \u010fal\u0161ieho druhu vo\u013ene \u017eij\u00facich m\u00e4so\u017eravcov, vlka drav\u00e9ho. DNA p\u00e1somnice E. multilocularis bola zaznamenan\u00e1 v 35,5 % zo 133 vy\u0161etren\u00fdch trusov. Navy\u0161e, pozit\u00edvne zvierat\u00e1 poch\u00e1dzali zo v\u0161etk\u00fdch \u0161tyroch sledovan\u00fdch lokal\u00edt \u2013 Chr\u00e1nenej krajinnej oblasti Po\u013eana (29,7 %), N\u00e1rodn\u00e9ho parku (NP) Mur\u00e1nska planina (51,2 %), NP Poloniny (20,0 %) a TANAPu (23,8 %), \u010do sved\u010d\u00ed o plo\u0161nom roz\u0161\u00edren\u00ed tohto parazita v popul\u00e1cii vlka na Slovensku(7). Nezanedbate\u013en\u00fd je v\u0161ak aj v\u00fdskyt parazita u psov. Zo 135 trusov zvierat poch\u00e1dzaj\u00facich z r\u00f4znych lokal\u00edt a chovate\u013esk\u00fdch podmienok, bola DNA E. multilocularis potvrden\u00e1 v 2 (1,4 %) trusoch, pri\u010dom obidva pozit\u00edvne jedince poch\u00e1dzali zo segregovan\u00fdch os\u00e1d na v\u00fdchodnom Slovensku(8).<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Z\u00e1ver<\/strong><\/p>\n<p>V\u00fdsledky sledovan\u00ed potvrdzuj\u00fa, \u017ee alveol\u00e1rna echinokok\u00f3za a jej p\u00f4vodca E. multilocularis s\u00fa na Slovensku pr\u00edtomn\u00e9, pri\u010dom okrem l\u00ed\u0161ok zohr\u00e1vaj\u00fa v \u0161\u00edren\u00ed p\u00e1somnice v\u00fdznamn\u00fa \u00falohu aj vlky a psi a po\u010det nakazen\u00fdch \u013eud\u00ed pomaly, ale neust\u00e1le st\u00fapa. Preto by odborn\u00e1 aj laick\u00e1 verejnos\u0165 mali by\u0165 informovan\u00e9 o rizik\u00e1ch a sp\u00f4soboch \u0161\u00edrenia ochorenia u \u013eud\u00ed, ako aj o vhodn\u00fdch prevent\u00edvnych opatreniach.<\/p>\n<p><strong>Po\u010fakovanie:<\/strong> V\u00fdskum bol finan\u010dne podporen\u00fd projektami APVV-15-0114 a VEGA 2\/0107\/20.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Literat\u00fara<\/strong><\/p>\n<p>1. Kin\u010dekov\u00e1 J, Reiterov\u00e1 K, Dubinsk\u00fd P, et al. A second case of autochthonous human alveolar echinococcosis in the Slovak Republic. Helminthologia 2002; 39: 193-196.<br \/>\n2. Kin\u010dekov\u00e1 J, Auer H, Reiterov\u00e1 K, et al. The first case of autochtonous human alveolar echinococcosis in the Slovak Republic (Case report). Mitteilungen der \u00d6sterreichischen Gesellschaft f\u00fcr Tropenmedizin und Parasitologie 2001; 23: 33-38.<br \/>\n3. Kern P, Bardonet K, Renner E, et al. European Echinococcosis Registry: Human alveolar echinococcosis, Europe, 1982 \u2013 2000. Emerging Infectious Diseases 2003; 9: 343-349.<br \/>\n4. Yang YR, Sun T, Li T, et al. Community surveys and risk factor analysis of human alveolar and cystic echinococcosis in Ningxia Hui Autonomous Region, China. Bulletin of Word Health Organisation 2006; 84: 714-721.<br \/>\n5. Antolov\u00e1 D, Miterp\u00e1kov\u00e1 M. Experience of Echinococcosis Control Programme in Slovakia. OIE\/WHO Sub-regional Workshop on Echinococcosis. Bishkek, Kyrgyzstan, 10 \u2013 11 December 2019.<br \/>\n6. Miterp\u00e1kov\u00e1 M, Dubinsk\u00fd P. Fox tapeworm (Echinococcus multilocularis) in Slovakia \u2013 summarizing long-term monitoring. Helminthologia 2011; 48: 155-161.<br \/>\n7. Jaro\u0161ov\u00e1 J, Antolov\u00e1 D, Guimar\u00e3es N, et al. Vlk drav\u00fd (Canis lupus) \u2013 \u010fal\u0161\u00ed rezervo\u00e1r Echinococcus multilocularis na Slovensku. Infovet 2019; 3: 124-127.<br \/>\n8. Jaro\u0161ov\u00e1 J, Antolov\u00e1 D. Intestin\u00e1lne parazity psov so zameran\u00edm na zoon\u00f3zne druhy. Vet\u017eurn\u00e1l 2020; 18: 20-24.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>*All tables, charts, graphs and pictures that are featured in this article can be found in the .pdf attachment at the end of the paper. &nbsp; Alveol\u00e1rna echinokok\u00f3za u \u013eud\u00ed na Slovensku Prv\u00e9 dva pr\u00edpady ochorenia \u010dloveka boli na Slovensku zaznamenan\u00e9 v roku 2000 a 2002(1,2). N\u00e1sledne do\u0161lo k postupn\u00e9mu n\u00e1rastu incidencie ochorenia, pri\u010dom do<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"footnotes":""},"categories":[1596],"tags":[1693,1690,1691,1694,1692],"class_list":["post-2200","post","type-post","status-publish","format-standard","hentry","category-parazitologia-en","tag-alveolar-echinococcosis","tag-alveolarna-echinokokoza-en","tag-echinococcus-multilocularis-en","tag-parasitic-infection","tag-parazitarna-infekcia-en","typ_clanku-review-article"],"acf":{"abstrakt":"<p>Alveolar echinococcosis (AE) caused by small tapeworm Echinococcus multilocularis belongs among the most severe parasitic diseases transmissible between animals and humans. The disease is characterized by the formation of cystic lesions in the liver or other organs. Lesions are vaguely defined from the adjacent tissues, form metastases, and their growth is infiltrative. Alveolar echinococcosis and its etiological agent occur in Slovakia since 2000. Since then, 80 human cases have been diagnosed at the Institute of Parasitology SAS and their number slowly, but continuously rises. Moreover, extensive epidemiological research confirmed the presence of E. multilocularis in free-living (red foxes, wolves) and domestic (dogs) carnivores throughout the country, with highly endemic localities in northern districts of Slovakia, where the prevalence of the parasite in red foxes reaches 60 %.<\/p>\n<p><strong>Keywords:<\/strong> Alveolar echinococcosis, Echinococcus multilocularis, parasitic infection<\/p>\n","casopis":[{"ID":2132,"post_author":"7","post_date":"2020-09-04 08:09:57","post_date_gmt":"2020-09-04 06:09:57","post_content":"SUPPLEMENT\r\n\r\nPri pr\u00edle\u017eitosti odbornej konferencie\r\n\r\n<strong>I. Aktu\u00e1lne probl\u00e9my hum\u00e1nnej parazitol\u00f3gie<\/strong>\r\n<ul>\r\n \t<li>Diagnosis of rickettsial infection using ELISA test developed at BMC SAS: Comparison to commercial tests on samples of patients from Slovakia<\/li>\r\n \t<li>Monitoring and diagnostics of intestinal parasitoses in children from a segregated settlement<\/li>\r\n \t<li>Prevention of toxoplasmosis in pregnancy in Slovakia<\/li>\r\n \t<li>Global changes and their impact on the occurrence of parasitosis in Slovakia<\/li>\r\n<\/ul>","post_title":"newsLab","post_excerpt":"","post_status":"publish","comment_status":"closed","ping_status":"closed","post_password":"","post_name":"newslab-6","to_ping":"","pinged":"","post_modified":"2020-09-04 13:36:36","post_modified_gmt":"2020-09-04 11:36:36","post_content_filtered":"","post_parent":0,"guid":"https:\/\/www.newslab.sk\/casopis\/newslab-6\/","menu_order":0,"post_type":"casopis","post_mime_type":"","comment_count":"0","filter":"raw"}],"strana":"102 - 103","upload_clanok":{"ID":2198,"id":2198,"title":"NEWSLAB_2-2020_PrP_Antolova_102_103str","filename":"NEWSLAB_2-2020_PrP_Antolova_102_103str.pdf","filesize":548011,"url":"https:\/\/www.newslab.sk\/wp-content\/uploads\/2020\/09\/NEWSLAB_2-2020_PrP_Antolova_102_103str.pdf","link":"https:\/\/www.newslab.sk\/en\/alveolar-echinococcosis-in-slovakia\/newslab_2-2020_prp_antolova_102_103str-2\/","alt":"","author":"7","description":"","caption":"","name":"newslab_2-2020_prp_antolova_102_103str-2","status":"inherit","uploaded_to":2200,"date":"2020-09-08 06:45:47","modified":"2020-09-08 06:45:47","menu_order":0,"mime_type":"application\/pdf","type":"application","subtype":"pdf","icon":"https:\/\/www.newslab.sk\/wp-includes\/images\/media\/document.png"}},"_links":{"self":[{"href":"https:\/\/www.newslab.sk\/en\/wp-json\/wp\/v2\/posts\/2200","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.newslab.sk\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.newslab.sk\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.newslab.sk\/en\/wp-json\/wp\/v2\/users\/7"}],"replies":[{"embeddable":true,"href":"https:\/\/www.newslab.sk\/en\/wp-json\/wp\/v2\/comments?post=2200"}],"version-history":[{"count":0,"href":"https:\/\/www.newslab.sk\/en\/wp-json\/wp\/v2\/posts\/2200\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.newslab.sk\/en\/wp-json\/wp\/v2\/media?parent=2200"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.newslab.sk\/en\/wp-json\/wp\/v2\/categories?post=2200"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.newslab.sk\/en\/wp-json\/wp\/v2\/tags?post=2200"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}