{"id":2206,"date":"2020-09-08T12:01:19","date_gmt":"2020-09-08T10:01:19","guid":{"rendered":"https:\/\/www.newslab.sk\/epidemiologia-dirofilariozy-na-slovensku\/"},"modified":"2020-09-08T12:13:20","modified_gmt":"2020-09-08T10:13:20","slug":"epidemiology-of-dirofilariosis-in-slovakia","status":"publish","type":"post","link":"https:\/\/www.newslab.sk\/en\/epidemiology-of-dirofilariosis-in-slovakia\/","title":{"rendered":"Epidemiology of dirofilariosis in Slovakia"},"content":{"rendered":"

*All tables, charts, graphs and pictures that are featured in this article can be found in the .pdf attachment at the end of the paper.<\/strong><\/span><\/p>\n

 <\/p>\n

Dirofilari\u00f3za u psov na Slovensku (2007-2019)<\/strong><\/p>\n

V obdob\u00ed rokov 2007 a\u017e 2019 bolo na dirofilari\u00f3zu vy\u0161etren\u00fdch 5 789 psov zo v\u0161etk\u00fdch okresov Slovenska. Priemern\u00e1 prevalencia Dirofilaria spp. dosiahla 9,88 %, s najni\u017e\u0161\u00edm po\u010dtom nakazen\u00fdch jedincov v \u017eilinskom a pre\u0161ovskom kraji (2 %, resp. 4 %) a najvy\u0161\u0161\u00edmi hodnotami, na \u00farovni pribli\u017ene 20 %, v nitrianskom a trnavskom kraji(1). Jednozna\u010dne dominantn\u00fdm druhom cirkuluj\u00facim na \u00fazem\u00ed Slovenska je D. repens s priemernou prevalenciou u psov 10,66 %; 39 psov (0,67 %) bolo nakazen\u00fdch druhom D. immitis, zmie\u0161an\u00e1 forma infekcie oboma druhmi bola potvrden\u00e1 u 31 (0,54 %) vy\u0161etren\u00fdch zvierat. D\u00f4le\u017eit\u00fdm zisten\u00edm je fakt, \u017ee od roku 2017 doch\u00e1dza k signifikantn\u00e9mu n\u00e1rastu infekci\u00ed sp\u00f4soben\u00fdch druhom D. immitis, pri\u010dom boli zaznamenan\u00e9 aj pr\u00edpady s fat\u00e1lnym koncom(2). V\u00e4\u010d\u0161ina pr\u00edpadov p\u013e\u00facnej (srdcovej) dirofilari\u00f3zy bola diagnostikovan\u00e1 v okrese Kom\u00e1rno. Vzh\u013eadom na to, \u017ee mikrofilaremick\u00e9 nelie\u010den\u00e9 jedince s\u00fa hlavn\u00fdm prame\u0148om n\u00e1kazy nielen pre ostatn\u00e9 psy, ale aj pre \u013eudsk\u00fa popul\u00e1ciu, treba apelova\u0165 na praktick\u00fdch veterin\u00e1rnych lek\u00e1rov, aby testovanie na dirofialari\u00f3zu zaradili medzi rutinn\u00e9
\nprevent\u00edvne vy\u0161etrenia a prispeli tak k obmedzeniu \u010fal\u0161ieho \u0161\u00edrenia parazita.<\/p>\n

 <\/p>\n

\u013dudsk\u00e9 pr\u00edpady dirofilari\u00f3zy na Slovensku (2007-2019)<\/strong><\/p>\n

Prv\u00fd autocht\u00f3nny pr\u00edpad dirofilari\u00f3zy u \u010dloveka na Slovensku bol diagnostikovan\u00fd v roku 2007(3). Do konca roka 2019 pracovn\u00edci Parazitologick\u00e9ho \u00fastavu SAV v Ko\u0161iciach a spolo\u010dnosti MEDIREX GROUP v Bratislave registrovali spolu 20 pr\u00edpadov infekcie, pri ktor\u00fdch bola pr\u00edtomnos\u0165 parazita potvrden\u00e1 morfologicky, histologicky a\/alebo anal\u00fdzou DNA. Z\u00e1rove\u0148 s\u00fa evidovan\u00e9 \u010fal\u0161ie pr\u00edpady na z\u00e1klade hl\u00e1senia lek\u00e1rov, av\u0161ak bez mo\u017enosti anal\u00fdzy biologick\u00e9ho materi\u00e1lu. U 15 pacientov bola diagnostikovan\u00e1 subkut\u00e1nna forma dirofilari\u00f3zy, v niektor\u00fdch pr\u00edpadoch aj s potvrden\u00fdm syndr\u00f3mom larva migrans cutanea(4), v 4 pr\u00edpadoch bol p\u00f4vodca lokalizovan\u00fd v spojivkovom vaku, a registrovan\u00fd bol aj pr\u00edpad vz\u00e1cnej formy p\u013e\u00facnej infekcie(4). Vo v\u0161etk\u00fdch t\u00fdchto pr\u00edpadoch bol ako p\u00f4vodca ochorenia identifikovan\u00fd druh D. repens. Vekov\u00e9 rozp\u00e4tie infikovan\u00fdch \u013eud\u00ed sa pohybovalo od 3 do 71 rokov (14 mu\u017ei a 6 \u017eien). V\u00e4\u010d\u0161ina nakazen\u00fdch poch\u00e1dzala z regi\u00f3nov juhoz\u00e1padn\u00e9ho Slovenska (Bratislavsk\u00fdkraj \u2013 5 pacientov, Nitriansky kraj \u2013 5 pacientov, Trnavsk\u00fd kraj \u2013 3 pacienti), traja \u013eudia s potvrdenou dirofilari\u00f3zou boli z Pre\u0161ovsk\u00e9ho kraja, a po dvoch infikovan\u00fdch sme registrovali v Ko\u0161ickom a \u017dilinskom kraji. S prihliadnut\u00edm na epidemiologick\u00fa situ\u00e1ciu vo v\u00fdskyte dirofilari\u00f3zy v popul\u00e1cii psov, a hlavne aktu\u00e1lne r\u00fdchlo sa \u0161\u00edriaci druh D. immitis, ktor\u00fd je zodpovedn\u00fd za p\u013e\u00facnu formu ochorenia, treba sa zamera\u0165 na v\u00fdvoj a \u0161tandardiz\u00e1ciu citliv\u00fdch diagnostick\u00fdch postupov vyu\u017eite\u013en\u00fdch v be\u017enej medic\u00ednskej aj veterin\u00e1rnej laborat\u00f3rnej praxi.<\/p>\n

Po\u010fakovanie:<\/strong> V\u00fdskum bol podporen\u00fd finan\u010dn\u00fdmi prostriedkami projektu APVV-15-0114.<\/p>\n

Konflikt z\u00e1ujmov:<\/strong> Autori vyhlasuj\u00fa, \u017ee nemaj\u00fa \u017eiadny konflikt z\u00e1ujmov.<\/p>\n

 <\/p>\n

Literat\u00fara<\/strong>
\n1. Miterp\u00e1kov\u00e1 M, Igl\u00f3dyov\u00e1 A, \u010cabanov\u00e1 V, et al. Canine dirofilariosis endemic in Central Europe \u2013 10 years of epidemiological study in Slovakia. Parasitology Research 2016; 116(6): 2389-2395.
\n2. Miterp\u00e1kov\u00e1 M, Zborovsk\u00e1 H, Bielik B, et al. The fatal case of an autochthonous heartworm disease in a dog from a non-endemic region of south-eastern Slovakia. Helminthologia 2020; 57(2): in press.
\n3. Bab\u00e1l P, Kobzov\u00e1 D, Nov\u00e1k I, et al. First case of cutaneous human dirofilariosis in Slovak Republic. Bratislava Medical Journal 2008; 109(11): 486-488.
\n4. Miterp\u00e1kov\u00e1 M, Antolov\u00e1 D, Ondriska F, et al. Human Dirofilaria repens infections diagnosed in Slovakia in the last 10 years (2007-2017). Wiener Klinische Wochenschrift 2017; 129 (17-18): 634-641.<\/p>\n","protected":false},"excerpt":{"rendered":"

*All tables, charts, graphs and pictures that are featured in this article can be found in the .pdf attachment at the end of the paper.   Dirofilari\u00f3za u psov na Slovensku (2007-2019) V obdob\u00ed rokov 2007 a\u017e 2019 bolo na dirofilari\u00f3zu vy\u0161etren\u00fdch 5 789 psov zo v\u0161etk\u00fdch okresov Slovenska. Priemern\u00e1 prevalencia Dirofilaria spp. dosiahla 9,88<\/p>\n","protected":false},"author":7,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_mi_skip_tracking":false,"footnotes":""},"categories":[1596],"tags":[1702,1701,1703],"class_list":["post-2206","post","type-post","status-publish","format-standard","hentry","category-parazitologia-en","tag-dirofilaria-zoonoses","tag-dirofilariosis","tag-parasitic-infections","typ_clanku-review-article"],"acf":{"abstrakt":"

Human dirofilariosis, a mosquito-borne infection caused by Dirofilaria nematodes, is currently considered to be an emerging zoonosis in the territory of the Central Europe. Climate changes, and pets\u2019 travelling and trade play a crucial role in the infection spreading. In Slovakia, the first epidemiological research initiated in 2007 revealed dirofilariosis in dog population with prevalence ranged between 2.0 % in the northern region and more than 25.0 % in the south-western part of the country. Dirofilaria repens, responsible for a subcutaneous form of the diseases, was confirmed as a dominant causative agent. The first human case of autochthonous dirofilariosis in Slovakia was diagnosed in 2007. Since then, more than 20 human cases have been registered, including subcutaneous, ocular, and pulmonary dirofilariosis all caused by D. repens species. The majority of those affected came from the southern regions of the country, bordering Austria and Hungary, which areconsidered to be endemic areas for canine dirofilariosis. However, some cases likely remain undiagnosed, seeing that physicians still miss sufficient experience with this infection.<\/p>\n

Keywords:<\/strong> Dirofilariosis, Dirofilaria; Zoonoses, Parasitic infections<\/p>\n","casopis":[{"ID":2132,"post_author":"7","post_date":"2020-09-04 08:09:57","post_date_gmt":"2020-09-04 06:09:57","post_content":"SUPPLEMENT\r\n\r\nPri pr\u00edle\u017eitosti odbornej konferencie\r\n\r\nI. Aktu\u00e1lne probl\u00e9my hum\u00e1nnej parazitol\u00f3gie<\/strong>\r\n