Article type :
Tumour genesis is accompanied by the activation of antitumour immunity, which has the potential to influence the biological behaviour of the tumour. The present study...
Vaccine vulnerabilities: can we prevent them? – SARS-CoV-2 case study
Michaela Hýblová, Patrik Krumpolec, Klaudia Babišová, Gabriel Minárik
The discovery of antibiotics by Alexander Fleming and the introduction of vaccination are undoubtedly among the most remarkable medical milestones in modern human history. In...
Keywords: ADE, COVID-19, mRNA vaccines; COVID 19, mRNA vakcíny, VITT
Whole-genome sequencing methods for CNV detection
Zuzana Klinovská, Marcel Kucharik, Jaroslav Budiš, Tomáš Szemes
The importance of copy number variants (CNVs) in reference to human health is rising continuously. They are linked to various types of disorders, syndromes and...
Extracellular mitochondrial DNA as a non-invasive biomarker of cancer
Silvia Bokorová, Katarína Suroviaková, Ondrej Pös, Werner Krampl, Mgr. Jakub Styk, Tomáš Szemes
Mitochondria play an essential role in the energy metabolism of cells and thus affect essential cellular functions possibly associated with cancer development. Mitochondrial DNA (mtDNA)...
Keywords: biomarker, cf-mtDNA, heteroplasmy, mitochondria