Environmental oestrogen bisphenol A and disorders in woman fertility

Abstract:

Prevalence of male and female fertility disorders is very high, affecting approximately 10-15% of couples. Environmental factors contribute to this rapidly increasing tendency. The population is still more exposed to a variety of industrial chemical substances, mostly to the group of them called environmental oestrogens. Bisphenol A (BPA) is one of the most common. It is found in plastic bottles, food packages, pipes, clothes or certain types of paper. Due to its structural similarity to endogenous oestrogens BPA can interfere with physiological processes in the human organism, which leads to infertility. Its effects are influenced by time, length and intensity of exposure. The developmental stage is the most sensitive period when even small doses can leave irreversible consequences on fertility.

Keywords: Bisphenol A, environmental oestrogens, infertility, ovary, xenoestrogens

 

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