Prevalence and antimicrobial susceptibility of Ureaplasma urealyticum and Mycoplasma hominis isolated from genital and urinary samples examined in the period 2014-2017 in KNsP Čadca

Abstract:

Urogenital mycoplasmas and ureaplasmas, namely Mycoplasma hominis (M. hominis) and Ureaplasma urealyti­cum (U. urealyticum) are opportunistic bacterial pathogens causing urogenital infections in children and adults. The aim of this study was to evaluate the prevalence and antimicrobial susceptibility of M. hominis and U. urea­lyticum isolated from genital and urinary samples examined during the period 2014-2017 in KNsP Čadca.

The results show that the presence of these microorganisms in the pathogenesis of urogenital infections is most common in fertile age in women and in men aged over 60 years. Of the total of 4736 investigated biological sam­ples, the incidence of urogenital mycoplasmas and ureaplasmas was recorded in 1,308 patients, representing 27.6% (23.7% for women and 3.9% for males). Most commonly U. urealyticum was identified, 77.6%, less M. ho­minis, only 4.5%. The presence of both microorganisms was demonstrated in 17.9% of the tested samples. All urogenital mycoplasmas and ureaplasmas identified, have been tested to selected groups of antimicrobials that have therapeutic significance in their treatment. They are macrolide and tetracycline antibiotics, second and third generation quinolones, linkozamides (clindamycin) and streptogramins (pristinamycin).

Tetracycline antibiotics, for example doxycycline, may be recommended in therapy for the tested population from the catchment area of KNsP Čadca.

Keywords: antimicrobial susceptibility, Ureaplasma urealyticum, Mycoplasma hominis

*All tables, charts, graphs and pictures that are featured in this article can be found in the .pdf attachment at the end of the paper.