Lynch syndrome (LS), or hereditary non-polyposis colorectal cancer (HNPCC), is an autosomal dominant disease in which mutations occur in genes for MMR proteins responsible for...
Microsatellite instability (MSI) is a state of genomic alteration occurring in the region of microsatellites, usually formed by 1 – 6 nucleotide repeats, which accumulate...
Lynch syndrome is the most common cause of hereditary colorectal carcinoma and the population of males in Slovakia have the highest incidence worldwide. Molecular methods...